Chemical constituents of Croton oblongifolius Roxb. stem bark from Amphoe Phurua, Loei Province

Abstract

The ground air-dried stem bark of Croton oblongifolius Roxb. collected from Amphur Phurua, Loei Province was extracted subsequently with hexane, ethyl acetate and methanol. The solvents in each crude extract were evaporated by evaporation under reduced pressure to obtain crude hexane extract, crude ethyl acetate extract and crude methanol extract, respectively. Each crude extract was separated and purified using column chromatographic technique. Five compounds were found. There were Crotocembraneic acid (1) Neocrotocembraneic acid (2) Kolavenol (3) Hardwickiic acid (4) and Nasimalun A (5), respectively. The structure of these compounds were characterized using their physical and chemical properties and spectral data.