Alkaloids from the leaves of Alstonia macrophylla

Abstract

Four pure compounds were isolated from the leaves of Alstonia macrophylla Wall. ex G. Don. Three of them were indole alkaloids identified as two vincorine groups namely demethoxyalstonamide and (-)-1-norvincorine and another one of indole alkaloids as macroline group, being alstophylline. The last one was amide namely 3,4,5-trimethoxybenzamide. The structures of all isolated compounds were determined by extensive spectroscopic studies, including comparison of UV, IR, MS and NMR spectra with the previously reported data.