Preparation of proanthocyanidin nanoparticles from grape seed extract

Abstract

In this experiment, we aimed to synthesize the proanthocyanidin nanoparticles from grape seed extract (GSE) with and without encapsulating calcium citrate by coprecipitation method. The concentrations of GSE, calcium ion, and citrate ion were varied to specify the suitable proportion that nanoparticles can be formed. UV-Vis spectrophotometer and scanning electron microscope were used to characterize the shape and size of nanoparticles. However, the size of the particles was not in the nanoscale. Therefore, further development is needed to successfully synthesize the proanthocyanidin nanoparticles.